Severe mosquito bite allergy: an unusual EBV+ NK cell lymphoproliferative disorder
نویسندگان
چکیده
منابع مشابه
[Senile EBV-associated B-cell lymphoproliferative disorder].
Epstein-Barrvirus (EBV)は1964年 にアフリカのバー キットリンパ腫培養細胞から発見された.そ の後,上 咽頭 がんや 胃がんなどとの関わ りも明らかにされ,歴 史的に最 も活発 に研究 がな されて きた ヒ トがん ウイルスhuman Cancer virusで あると言える.そ の明 らかな発癌 との関連 にも関わらず,EBVは 高度に普遍的なウイルスで もある. EBVは 主に唾液 を関した母子感染によって伝播 されると 考えられる.わ が国の25歳 以上の成人人口においては,ほ ぼ100%に 近い感染率を示す とされる. EBVと 血 液 リ ンパ 系 疾 患 との 関 わ りは 深 い.表1に, 主 なEBV関 連 血 液 リ ンパ 系 疾 患 を示 す.知 られ る 限 り リ ンパ 系 疾 患 が 主 体 で あ り,顆 粒 球 系 な ど他 ...
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Epstein Barr virus (EBV)-related hemophagocytic lymphohistiocytosis (EBV-HLH) is a form of acquired, infection-related HLH which typically represents a fulminant presentation of an acute EBV infection of CD8+ T cells with 30-50% mortality rate. Systemic EBV-positive lymphoproliferative disease of childhood (SE-LPD) is a rare T cell lymphoproliferative disorder predominantly arising in the setti...
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ژورنال
عنوان ژورنال: Blood
سال: 2019
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2018-11-886341